If you live in the UK and like to knit, crochet or sew and want to make something for charity , then Loving Hands is the charity you need to look at ( http://www.lovinghands.org.uk/ ). They support a whole variety of charities around the world and Lou their wonderful leader does an amazing job of making sure each and every item you make gets to the right place where it is needed. There are three monthly challenges which you can make items for if you wish, or you can just make the items that are always needed. Basically you can make what you want, when you want and know that it will be sent to a good home.
They are based in Scotland but have satelite support groups in other parts of the UK too. If you are unsure about anything, there is a forum where you can ask questions and you will be guaranteed a warm and friendly welcome.